Question
Download Solution PDFPyruvic acid before combining with oxaloacetic acid of citric acid cycle becomes
This question was previously asked in
UP TGT Biology 2010 Official Paper
Answer (Detailed Solution Below)
Option 4 : Acetyl Co-A
Free Tests
View all Free tests >
UP TGT Arts Full Test 1
7.1 K Users
125 Questions
500 Marks
120 Mins
Detailed Solution
Download Solution PDFExplanation:
- Pyruvate or pyruvic acid, which is formed by the glycolytic catabolism of carbohydrates in the cytosol, after it enters the mitochondrial matrix undergoes oxidative decarboxylation by a complex set of reactions catalyzed by pyruvic dehydrogenase.
- The reactions catalyzed by pyruvic dehydrogenase require the participation of several coenzymes, including NAD+ and Coenzyme A. This process is called Link reaction or gateway reaction.
- During this process, two molecules of NADH are produced from the metabolism of two molecules of pyruvic acid (produced from one glucose molecule during glycolysis)
- The acetyl CoA then enters a cyclic pathway, the citric acid cycle more commonly called Krebs’ cycle after the scientist Hans Krebs who first elucidated it.
- Thus, Pyruvic acid before combining with oxaloacetic acid of the citric acid cycle becomes Acetyl CoA
Additional Information
- Under anaerobic conditions, the pyruvic acid undergoes partial oxidation to form lactic acid. This process is catalyzed by the enzyme lactate dehydrogenase
- During the Kreb's cycle, Acetyl CoA condenses with Oxaloacetic acid to form Citric acid. This Citric acid is then converted into Cis Aconitic acid in the presence of enzyme Aconitase.
Last updated on May 6, 2025
-> The UP TGT Exam for Advt. No. 01/2022 will be held on 21st & 22nd July 2025.
-> The UP TGT Notification (2022) was released for 3539 vacancies.
-> The UP TGT 2025 Notification is expected to be released soon. Over 38000 vacancies are expected to be announced for the recruitment of Teachers in Uttar Pradesh.
-> Prepare for the exam using UP TGT Previous Year Papers.