Platelets contain an enzyme which has an important role in clotting of blood. This enzyme is known as

Question

Question

This question was previously asked in

ISRO Pharmacist Previous Year Question paper 2017

Answer 1

Correct Answer: Thrombokinase

Rationale:

Platelets contain an enzyme called thrombokinase, also known as thromboplastin. This enzyme plays a crucial role in the clotting of blood by converting prothrombin to thrombin in the presence of calcium ions, which is a key step in the coagulation cascade.
Thrombin then acts to convert fibrinogen, a soluble plasma protein, into fibrin strands that form a stable blood clot. This process is essential for stopping bleeding and initiating wound healing.

Explanation of Other Options:

Cholinesterase

Rationale: Cholinesterase is an enzyme that breaks down acetylcholine, a neurotransmitter, in the synaptic cleft. It is not involved in the blood clotting process but rather in the regulation of nerve impulses.

Transaminase

Rationale: Transaminases are enzymes that catalyze the transfer of amino groups from one molecule to another. These enzymes are primarily involved in amino acid metabolism and liver function, not in blood clotting.

Decarboxylase

Rationale: Decarboxylases are enzymes that catalyze the removal of a carboxyl group from amino acids and other compounds. They play a role in various metabolic pathways, but they are not involved in the blood clotting process.

Conclusion:

Thrombokinase is the enzyme found in platelets that is essential for the blood clotting process. It initiates a series of reactions that lead to the formation of a stable blood clot, which is critical for stopping bleeding and promoting wound healing. The other enzymes listed have distinct functions unrelated to blood coagulation.

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