A chain of peptide containing linear sequences of amino acid linked by peptide bonds best represent the

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  1. Primary structure
  2. Secondary structure
  3. Tertiary structure
  4. Quaternary structure

Answer (Detailed Solution Below)

Option 1 : Primary structure
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The correct answer is Primary Structure

Concept:

  • Proteins are complex biomolecules made up of amino acids that play vital roles in various biological processes.
  • The structure of proteins is categorized into four levels: primary, secondary, tertiary, and quaternary structures, each representing different aspects of protein organization.
  • The primary structure of a protein refers to the specific linear sequence of amino acids linked together by peptide bonds.

Explanation:

Primary Structure:

  • The primary structure is the linear arrangement of amino acids in a polypeptide chain.
  • Amino acids are linked by peptide bonds, which are covalent bonds formed between the carboxyl group of one amino acid and the amino group of another.
  • This sequence is unique to each protein and determines its overall structure and function.

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Secondary Structure:

  • The secondary structure refers to the folding of the polypeptide chain into regular structures such as alpha-helices and beta-pleated sheets, stabilized by hydrogen bonds.
  • It does not describe the linear sequence of amino acids but rather the local folding patterns.

Tertiary Structure:

  • The tertiary structure represents the overall three-dimensional shape of a single polypeptide chain.
  • It is stabilized by interactions such as hydrogen bonds, ionic bonds, hydrophobic interactions, and disulfide bonds between the side chains (R groups) of amino acids.

Quaternary Structure:

  • The quaternary structure refers to the arrangement and interaction of multiple polypeptide chains (subunits) in a multi-subunit protein.
  • Examples include hemoglobin, which consists of four subunits.
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